Publisher's Synopsis
The two volumes of C-1 Building Blocks in Organic Synthesis provide a critical overview of synthetic organic reactions that add one carbon atom to a substrate. The number of reagents available as C-1 building blocks is limited, but the reaction types that can be applied for each of them vary considerably. In this volume, additions of to alkenes are discussed. This includes reviews of hydroformylation, alkoxy- and hydroxycarbonylation, and hydrocyanation. Further sections describe cyclopropanation, and addition of carbon dioxide to alkenes, and selective conjugate addition reactions. Included also are reviews of carbonylation reactions of alkynes, and comprehensive overviews of the selective nucleophilic addition of C-1 reagents to carbonyl compounds and derivatives.
