Publisher's Synopsis
Resistance of microorganisms to multiple antibiotics and other drugs is a major problem throughout the world. Multidrug efflux is a process whereby a single transporter can remove a broad range of substrates from the cell thereby causing resistance to substances such as drugs and antibiotics. This book provides the first comprehensive overview of this phenomenon in microorganisms and contains reviews of the current research in this important field. With contributions from Internationally renown authors topics covered include genomic analysis of drug efflux pumps, the large scale knock-out of drug transporters, structure/function analysis of drug pumps, the inhibition of the efflux pump as a clinical approach, and much more. An essential text for all scientists with an interest in drug and antibiotic resistance in a range of different microorganisms.
