Publisher's Synopsis
Drugs in Context is an independent, peer reviewed and practice orientated review of all the significant data on a specific drug, placed in the context of the disease and clinical practice setting. Nateglinide; Editorial: "The overwhelming majority of cases of diabetes are now of the type 2 variety, and 80% of these patients will die (many prematurely) from cardiovascular disease." Disease Overview: "Type 2 diabetes may go undiagnosed for many years as hyperglycaemia may not be severe enough to provoke obvious symptoms of diabetes." Drug Review: "Nateglinide seems to be extremely effective in restoring physiological (early-phase) insulin secretion, and so is likely to be an effective postprandial glucose-lowering agent." Improving Practice: "Targeting individuals with states of impaired glucose metabolism may be beneficial as these groups have a higher risk of progressing to type 2 diabetes."