Publisher's Synopsis
Therapy of rheumatiod arthritis is undergoing dramatic chamges. Greater appreciation of the long-term outcomes of this disease and the impacts of treatments has resulted in a more aggressive approach to therapy, especially in the early stages.;An increasingly diverse array of anti-rheumatic drugs with novel effects on inflammation and the immune system confronts us. One factor remains constant; individual response to anti-rheumatic therapy is highly variable, thus providing an important approach to understanding the heterogeneity of the disease process, as well as the mechanisms of drug action.;Experts of international repute address in this volume relevant aspects of recent research into non-steroidal anti inflanunatory drugs, stereochemistry, pharmacodynamics and pharmacokinetics, trials and trial design, combination therapy, new and old disease-modifying anti-rheumatic drugs, adverse reactions, side effects. The result is a state-of-the-art review of anti-rheumatic drug therapy.;Variability in Response to Anti-Rheumatic Drugs is a valuable source of information for rheumatic disease researchers and pharmacologists, rheumatologists, as well as general physicians and internists.
