Animal Models of Pain

With the loss of work days, the price of health care and payments for compensation, litigation, and malpractice, and the overwhelming cost of human suffering, chronic pain syndromes affect humanity enormously on both an economic and personal level. In Animal Models of Pain, expert investigators in the field provide a consolidated review of the current state of pain research by capturing the diversity of animal models that are used to investigate pain mechanisms, which range from surgical incision to mechanical compression and from spinal cord injury to cutaneous/local inflammation and beyond. As a volume in the respected Neuromethods series, this book delivers its vital content through detailed descriptions of a wide variety of step-by-step laboratory methods. Authoritative and cutting-edge, Animal Models of Pain seeks to lead scientists closer to the ultimate goal of improving the quality of life and relieving the unbearable burden of chronic pain for millions of people throughout the world.

ISBN 1607618796   Pages 242 ISBN13 9781607618799 (What's this?)   Weight (grammes) 599 Publisher Humana Press Inc.   Published in Totowa, NJ Imprint Humana Press Inc.   Series title Neuromethods Format Hardback   Height (mm) 254 Publication date 11 Oct 2010   Width (mm) 178 DEWEY 616.04720724   Spine width (mm) 14 DEWEY edition DC22   Academic level Professional / Scholarly

		Preface
		Contributors
1		Assessment of Pain in Animals by Wenrui Xie		1
2		Animal Models of Inflammatory Pain by Ke Ren		23
3		Animal Models of Visceral Pain by Karin N. Westlund		41
4		Animal Models of Pain After Peripheral Nerve Injury by Chao Ma		69
5		Animal Models of Pain After Injury to the Spinal Ganglia and Dorsal Roots by Xue-Jun Song		81
6		Localized Inflammatory Irritation of the Lumbar Ganglia: An Animal Model of Chemogenic Low Back Pain and Radiculopathy by Jun-Ming Zhang		89
7		Animal Models of Central Neuropathic Pain by Louis P. Vera-Portocarrero		103
8		Animal Models of Cancer Pain by Alvin J. Beitz		117
9		Animal Models of Diabetic Neuropathic Pain by Joseph R. Stimers		147
10		Animal Models of HIV-Associated Painful Sensory Neuropathy by Fletcher A. White		171
11		Animal Models of Postoperative Pain by Timothy J. Brennan		181
		Index		201

From the reviews: "This book critically describes the recent attempts to more directly model prevalent clinical pain syndromes to increase face and predictive validity of pain modelling tools. The book encompasses a total of 11 chapters, each written by authoritative researchers in the field. ! Each chapter describes in detail how the models in question are developed. ! appeal to scientists interested in understanding pain mechanisms and in the preclinical development of new analgesics, as well as clinicians aiming at advancing translation pain research." (Debby Van Dam, Clinical Neurology and Neurosurgery, January, 2011)

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