Calcium in Human Health

This comprehensive review of the state of our knowledge concerning calcium not only demonstrates its importance to human health, but also defines its many complex roles. The authors summarize the latest basic scientific information on the cellular and metabolic functions of calcium, explaining the leading techniques for accurately measuring its bioavailability, absorption, and kinetics, and showing that calcium deficiency is a major problem while calcium excess a rare one. They also examine the complex regulation of calcium absorption, distribution, and excretion, as well as the multiple interactions of diet/lifestyle, and physical activity in calcium homeostasis. Their discussion of the specific roles of calcium in a variety of clinical disorders - osteoporosis, oral health, obesity, reproductive disorders, and the metabolic syndrome - provides new insights and raises new questions. The complex changes in calcium and phosphate regulation that occur in renal disease and the potential role of calcium in hypertension and vascular disease are also addressed.

ISBN 1588294528   Pages 472 ISBN13 9781588294524 (What's this?)   Volumes 1 Publisher Humana Press Inc.   Weight (grammes) 1031 Imprint Humana Press Inc.   Published in Totowa, NJ Format Hardback   Series title Nutrition and Health Publication date 01 Sep 2005   Height (mm) 254 Library of Congress 2005006564   Width (mm) 178 DEWEY 613.285   Spine width (mm) 25 DEWEY edition DC22   Academic level Professional / Scholarly

1		Introduction by Connie M. Weaver and Robert P. Heaney		1
2		Bone as the calcium nutrient reserve by Robert P. Heaney		7
3		Cellular functions and fluxes of calcium by Emmanuel M. Awumey and Richard D. Bukoski		13
4		Nutritional epidemiology : dietary assessment methods by Carol J. Boushey		39
5		Clinical approaches for studying calcium metabolism and its relationship to disease by Connie M. Weaver		65
6		Kinetic studies by Meryl E. Wastney and Yongdong Zhao and Connie M. Weaver		83
7		Requirements for what endpoint? by Robert P. Heaney and Connie M. Weaver		97
8		Dietary calcium : recommendations and intakes around the world by Anne C. Looker		105
9		Food sources, supplements, and bioavailability by Connie M. Weaver and Robert P. Heaney		129
10		The calcium economy by Robert P. Heaney		145
11		Molecular regulation of calcium metabolism by James C. Fleet		163
12		Influence of total diet on calcium homeostasis by Zamzam K. (Fariba) Roughead		191
13		Influence of lifestyle choices on calcium homeostasis : smoking, alcohol, and hormone therapies by D. Lee Alekel and Oksana Matvienko		209
14		Influence of physical activity on calcium and bone by Matthew Vukovich and Bonny Specker		227
15		The case for a calcium appetite in humans by Michael G. Tordoff		247
16		Infancy and childhood by Steven A. Abrams and Keli M. Hawthorne		269
17		Pre-puberty and adolescence by Connie M. Weaver		281
18		Calcium in pregnancy and lactation by Heidi J. Kalkwarf		297
19		Calcium in systemic human health by Robert P. Heaney		313
20		Calcium and oral health by Elizabeth A. Krall		319
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From the reviews: "This volume, part of the Series Nutrition and Health, reviews in 28 chapters divided into 6 sections, the latest scientific information on the cellular and metabolic functions and need of calcium. ! Each chapter has references ! . A well organized, easy readable text of great actual interest." (Pediatric Endocrinology Reviews, Vol. 4 (2), 2006-2007)

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