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T. Lang, F. Lang
ISBN: 9783805567374
Format: Hardback
Publisher:S Karger AG
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A compilation of reviews on cell volume regulation in health and disease. It covers such topics as mechanisms and signaling of cell volume regulation and the effect of cell volume on cell function, with emphasis on ion channels and transporters, kinases and gene expression.
This volume presents a unique compilation of reviews on cell volume regulation in health and disease, with contributions from leading experts in the field. The topics covered include mechanisms and signaling of cell volume regulation and the effect of cell volume on cell function, with special emphasis on ion channels and transporters, kinases and gene expression. Several chapters elaborate on how cell volume regulatory mechanisms participate in the regulation of epithelial transport, urinary concentration, metabolism, migration, cell proliferation and apoptosis. Last but not least, this publication is an excellent guide to the role of cell volume in the pathophysiology of hypercatabolism, diabetes mellitus, brain edema, hemoglobinopathies, tumor growth and metastasis, to name just a few. Providing deeper insights into an exciting area of research which is also of clinical relevance, this publication is a valuable addition to the library of those interested in cell volume regulation.
| ISBN | 3805567375 | | Pages | 264 | | ISBN13 | 9783805567374 (What's this?) | | Volumes | 001 | | Publisher | S Karger AG | | Weight (grammes) | 920 | | Imprint | S Karger AG | | Published in | Basel | | Format | Hardback | | Series editor | Berlyne, G.M., Ronco, C. | | Publication date | 14 Sep 1998 | | Series ISSN | 0302-514 | | Library of Congress | QP90.6.C43 | | Series title | Contributions to Nephrology S. | | DEWEY | 616.61 | | Height (mm) | 230 | | DEWEY edition | DC21 | | Academic level | Undergraduate, Postgraduate, Professional / Scholarly |
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| | | Preface | | | | | | Introduction to Cell Volume Regulatory Mechanisms by S. Waldegger and J. Matskevitch and G. L. Busch | | 1 | | | | Cell Volume-Regulated Cation Channels by F. Wehner | | 8 | | | | Cell Volume-Sensitive Chloride Channels by Y. Okada | | 21 | | | | Mechanisms of Osmolyte Release by R. K. H. Kinne | | 34 | | | | Sensors and Signal Transduction in the Activation of Cell Volume Regulatory Ion Transport Systems by E. K. Hoffmann and St. F. Pedersen | | 50 | | | | Activation of Protein Kinases upon Volume Changes: Role in Cellular Homeostasis by L. D. Shrode and E. Krump and S. Grinstein | | 79 | | | | Intracellular Signaling in Response to Osmotic Stress by D. Kultz and M. B. Burg | | 94 | | | | Approaches to Identifying Cell Volume-Regulated Genes by A. Chevaile and B. Santos and J. Randall | | 110 | | | | The Cytoskeleton in Cell Volume Regulation by A. Moustakas and P. A. Theodoropoulos and A. Gravanis | | 121 | | | | Cell Volume Regulatory Ion Transport in Cell Migration by M. Ritter | | 135 | | | | Cell Volume in Cell Proliferation and Apoptotic Cell Death by F. Lang and A. Lepple-Wienhues and I. Szabo | | 158 | | | | Cellular Osmoregulation in Kidney Medulla by F.-X. Beck and W. G. Guder and M. Schmolke | | 169 | | | | Osmoregulation of Liver Cell Function: Signalling, Osmolytes and Cell Heterogeneity by D. Haussinger | | 185 | | | | Volume Regulation and 'Cross-Talk' in Sodium-Absorbing Epithelial Cells by St. G. Schultz and W. P. Dubinsky and J.-Y. Lapointe | | 205 | | | | Pathophysiology of Abnormal Cell Volume in Human Red Cells by J. C. Ellory and J. S. Gibson and G. W. Stewart | | 220 | | | | Swelling-Activated Release of Excitatory Amino Acids in the Brain: Relevance for Pathophysiology by H. K. Kimelberg and A. A. Mongin | | 240 | | | | Author Index | | 258 | | | | Subject Index | | 259 |
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