Cholecystokinin

This volume reflects the interest in cholecystokinin, not only among gastroenterologists but also among neuroscientists and the drug industry, due to findings concerning the cholecystokinin antagonist and its effects on the central nervous system regarding satiety, panic attacks and depression.

ISBN 089766857X   Weight (grammes) 816 ISBN13 9780897668576 (What's this?)   Published in New York Publisher New York Academy of Sciences   Conference location Chatham, Massachusetts, USA Imprint New York Academy of Sciences   Conference name CCK 1993: International Symposium Format Hardback   Conference year 1993 Publication date 15 Apr 1994   Series ISSN 0077-892 Library of Congress Q11.N5 VOL   Series title Annals of the New York Academy of Sciences DEWEY 591.142   Height (mm) 230 DEWEY edition DC20   Width (mm) 165 Pages 475   Academic level Postgraduate, Professional / Scholarly

Part 1 Historical Perspectives on Cholecystokinin Research. Part 2 The Biochemistry and Molecular Biology of Cholecystokinin: Natural and Synthetic CCK-58; Novel Reagents for Studying Cholecystokinin Physiology; Regulation of Cholecystokinin Gene Expression in Rat Intestine; Peptides Related to Cholecystokinin in Nonmammalian Vertebrates; Is Invertebrate CCK-Like Immunoreactivity Caused by Asp-Phe-Amides Similar to the LymnaDFamides (A New Family of Molluscan Neuro-Peptides)?. Part 3 The Biochemistry and Molecular Biology of Cholecystokinin Receptors: Cellular Mechanisms Mediating Agonist-Stimulated Calcium Influx in the Pancreatic Acinar Cell; Cholecystokinin Receptor Family; Molecular Cloning, Structure, and Functional Expression in Rat, Guinea Pig and Human; The CCC-B/Gastrin Receptor; Identification of Amino Acids That Determine Nonpeptide Antagonist Affinity. Part 4 Pharmacology of Cholecystokinin and its Antagonists: Biological Evaluation of JMV180 Cholecystokinin Analogues; Distinguishing Multiple CCK Receptor Subtypes; Studies with Guinea Pig Chief Cells and Transfected Human CCK Receptors; Novel CCK Analogues for Studying CCK-B Receptor; The Ureidoacetamides, a Novel Family of Non-Peptide CCK-B/Gastrin Antagonists. Part 5 Neurophysiology of Cholecystokinin: CCK Elicits and Modulates Vagal Afferent Activity Arising from Gastric and Duodenal Sites; Ionic Mechanisms Underlying Cholecystokinin Action in Rat Brain; Cholecystokinin Modulates Dopamine-Mediated Behaviours; Differential Actions in Medial Posterior Versus Anterior Nucleus Accumbens; Integration of Postprandial Function in the Proximal Gastrointestinal Tract; Role of CCK and Sensory Pathways; CCK in Cerebral Cortex and the Spinal Level; Gastric Distention Induces C-Fos Immunoreactivity in the Rat Brain Stem; Feedback Inhibition of Cholecystokinin Secretion by Bile Acids and Pancreatic Proteases; Effects of CCK on Pancreatic Function and Morphology; Acid-Base Interactions During Exocrine Pancreatic Secretion; Primary Role for Ductal Bicarbonate in Acinar Lumen Function; Role of CCK in Gallbladder Function; Effect of Cholecystokinin on Gastric Motility in Humans; Effects of Dietary Fat on Postprandial Gastrointestinal Motility are Inhibited by a Cholecystokinin Type A Receptor Antagonist; Cholecystokinin and Satiety - a Time Line; Satiating Effect of Cholecystokinin; Brain Regions Where Cholecystokinin Exerts its Effect on Satiety; Endogenous CCK and the Peripheral Neural Substrates of Intestinal Satiety; Role of Cholecystokinin in the Regulation of Satiation and Statiety in Humans. (Part contents)

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