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Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7--hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action.
| ISBN | 0471969974 | | Pages | 358 | | ISBN13 | 9780471969976
(What's this?) | | Volumes | 000 | | Publisher | John Wiley and Sons Ltd | | Weight (grammes) | 682 | | Imprint | John Wiley & Sons Ltd | | Published in | Chichester | | Format | Hardback | | Height (mm) | 243 | | Publication date | 10 Mar 1997 | | Width (mm) | 167 | | Library of Congress | RM666.C76C | | Spine width (mm) | 25 | | DEWEY | 574.88 | | Academic level | Professional / Scholarly | | DEWEY edition | DC20 | |
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| | | List of Contributors | | | | | | Preface | | | | 1 | | History of the Development and Applications of Coumarin and Coumarin-related Compounds by Inge Weinmann | | 1 | | 2 | | The Chemistry and Occurrence of Coumarins by Gary J. Keating and Richard O'Kennedy | | 23 | | 3 | | The Metabolism of Coumarin by Olavi Pelkonen and Hannu Raunio and Arja Rautio | | 67 | | 4 | | The Effects of Coumarin and its Metabolites on Cell Growth and Development by Barbara Seliger | | 93 | | 5 | | Coumarin as an Immunomodulator by Gerhard J. Zlabinger | | 103 | | 6 | | The Mode of Entry of Coumarin into Cells and its Effects on Cell-Cell Communication and Migration by Kurt S. Zanker | | 125 | | 7 | | Coumarin in the Treatment of Lymphoedema and Other High-Protein Oedemas by John R. Casley-Smith and Judith R. Casley-Smith | | 143 | | 8 | | Mode of Action of Coumarin in the Treatment of Thermal Injuries by Neil B. Piller | | 185 | | 9 | | Renal Cell Carcinoma: The Background, Rationale and Current Development of Coumarin (1,2-benzopyrone) as a Potential Therapeutic Agent by Scot W. Ebbinghaus and James L. Mohler and M. Ernest Marshall | | 209 | | 10 | | The Potential Role of Coumarins in the Therapy of Prostate Cancer by James L. Mohler and Bernadette T. Williams and John A. Freeman | | 241 | | 11 | | Clinical and Biological Observations Associated with Coumarins by R. D. Thornes | | 255 | | 12 | | Analysis of Coumarins by Declan P. Bogan and Gary J. Keating and Heiko Reinartz | | 267 | | 13 | | Coumarins - Multifaceted Molecules with Many Analytical and Other Applications by Deirdre Cooke and Brian Fitzpatrick and Richard O'Kennedy | | 303 | | 14 | | Suggested Modes of Action of Coumarins and Some Comments on their Significance by Richard O'Kennedy and R. D. Thornes | | 333 | | | | Index | | 337 |
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