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Molecular and Cellular Biology
Klenk, Hans-Dieter Feldmann, Heinz Klenk, H. D.
H.D. Klenk, H. Feldmann
ISBN: 9780954523237
Format: Hardback
Publisher:Taylor & Francis Inc
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This book presents a comprehensive review of the current research on these highly virulent viruses. Topics covered include the genomics and molecular biology of filoviruses, pathogenesis, replication, epidemiology, pathogenicity, approaches to vaccine development, virus-host interactions and the immune response.
Ebola and Marburg viruses both cause severe haemorrhagic fevers. Much research has been performed in recent years on the molecular and genetic properties of these viruses and in particular has focused on molecular structure, replication and virus-host interactions. This book presents a comprehensive review of the current research on these highly virulent viruses. Topics covered include the genomics of the Filoviridae, molecular properties, taxonomy, replication, evolution, epidemiology, pathogenicity, virus-host interactions and the immune response.
| ISBN | 0954523237 | | Pages | 260 | | ISBN13 | 9780954523237
(What's this?) | | Volumes | 1 | | Publisher | Taylor & Francis Inc | | Weight (grammes) | 862 | | Imprint | Garland Publishing Inc | | Published in | CT | | Format | Hardback | | Previous ISBN | 9781898486428 | | Publication date | 18 Dec 2003 | | Height (mm) | 230 | | Library of Congress | QR201.E16 | | Spine width (mm) | 25 | | DEWEY | 579.256 | | Academic level | Professional / Scholarly | | DEWEY edition | DC22 | |
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| | | Contents | | | | | | Contributors | | | | | | Preface | | | | Ch. 1 | | Genome Organization, Replication, and Transcription of Filoviruses by Elke Muhlberger | | 1 | | Ch. 2 | | Structure of Viral Proteins by Winfried Weissenhorn | | 27 | | Ch. 3 | | Structural and Functional Polymorphism of the Glycoproteins of Filoviruses by Viktor E. Volchkov and Valentina A. Volchkova and Olga Dolnik and Heinz Feldmann and Hans-Dieter Klenk | | 59 | | Ch. 4 | | Molecular Mechanisms of Filovirus Entry by Stephen Y. Chan and Mark A. Goldsmith | | 91 | | Ch. 5 | | Roles of Filoviral Matrix- and Glycoproteins in the Viral Life Cycle by Gabriele Neumann and Takeshi Noda and Ayato Takada and Luke D. Jasenosky and Yoshihiro Kawaoka | | 137 | | Ch. 6 | | Virus Maturation by Larissa Kolesnikova and Stephen Becker | | 171 | | Ch. 7 | | Filovirus Pathogenesis in Nonhuman Primates by Thomas W. Geisbert and Peter B. Jahrling and Tom Larsen and Kelly J. Davis and Lisa E. Hensley | | 203 | | Ch. 8 | | Ebola Virus Infection in the Guinea Pig by Elena Ryabchikova and Margarita Smolina and Antonina Grajdantseva and Jurii Rassadkin | | 239 | | Ch. 9 | | Pathogenesis of Filovirus Infection in Mice by Mike Bray | | 255 | | Ch. 10 | | The Role of Endothelial Cells in Filovirus Hemorrhagic Fever by Hans-Joachim Schnittler and Ute Stroher and Tatiana Afanasieva and Heinz Feldmann | | 279 | | Ch. 11 | | Modulation of Innate Immunity by Filoviruses by Christopher F. Basler and Peter Palese | | 305 | | Ch. 12 | | Cellular and Molecular Mechanisms of Ebola Pathogenicity and Approaches to Vaccine Development by Gary J. Nabel and Nancy J. Sullivan and Zhi-Yong Yang | | 351 | | | | Index | | 367 |
.."."Extensively researched and well-written."."vol 7, no 12-E-Streams, December 2004 " An excellent reference for anyone doing research with these viruses as well as for educators in virology..""-Doody's Review Service, April 2004  Be the first to write a customer review
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