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Antibiotic Enzymes as Drugs and Therapeutics
Tomas G. Villa, Patricia Veiga Crespo
ISBN: 9780470376553
Format: Hardback
Publisher:John Wiley and Sons Ltd
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Enzybiotics, by using enzymes to fight bacteria, offer a novel and promising new way to combat infectious diseases. This book presents the state-of-the-art and therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, and biochemistry.
Enzybiotics, by using enzymes to fight bacteria, offer a novel and promising new way to combat infectious diseases. This book presents the state-of-the-art and therapeutic potential of enzybiotics, with a stress on therapeutic applications. The coverage offers a unique combination of medicinal chemistry, microbiology, genetics, and biochemistry. It also addresses the timely topic of bacterial resistance to antibiotics, and provides readers with a novel angle to study and combat infectious diseases.
| ISBN | 0470376554 | | Pages | 284 | | ISBN13 | 9780470376553
(What's this?) | | Weight (grammes) | 620 | | Publisher | John Wiley and Sons Ltd | | Published in | Chicester | | Imprint | Wiley-Blackwell (an imprint of John Wiley & Sons Ltd) | | Height (mm) | 244 | | Format | Hardback | | Width (mm) | 166 | | Publication date | 26 Jan 2010 | | Spine width (mm) | 24 | | DEWEY | 615.35 | | Academic level | Professional / Scholarly | | DEWEY edition | DC22 | |
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| 1 | | Enzybiotics and Their Potential Applications in Medicine by Jan Borysowski and Andrzej Gorski | | 1 | | 2 | | Advantages and Disadvantages in the Use of Antibiotics Or Phages as Therapeutic Agents by Patricia Veiga-Crespo and Tomas G. Villa | | 27 | | 3 | | Enzybiotics as Selective Killers of Target Bacteria by Juan C. Alonso and Marcelo E. Tolmasky | | 59 | | 4 | | Phylogeny of Enzybiotics by Patricia Veiga-Crespo and Tomas G. Villa | | 75 | | 5 | | Bacteriophage Lysins: The Ultimate Enzybiotic by Vincent A. Fischetti | | 107 | | 6 | | Bacteriophage Holins and Their Membrane Disrupting Activity by Marfa Gasset | | 123 | | 7 | | Anti-Staphylococcal Lytic Enzymes by Jan Borysowski and Andrzej Gorski | | 149 | | 8 | | Membrane-Targeted Enzybiotics by Marfa Gasset | | 173 | | 9 | | Design of Phage Cocktails for Therapy from a Host Range Point of View by Lawrence D. Goodridge | | 199 | | 10 | | Identifying Phage Lytic Enzymes: Past, Present, and Future by Jonathan E. Schmitz and Raymond Schuch and Vincent A. Fischetti | | 219 | | 11 | | Use of Genetically Modified Phages to Deliver Suicidal Genes to Target Bacteria by Lawrence D. Goodridge | | 253 | | | | Concluding Remarks: The Future of Enzybiotics by Patricia Veiga-Crespo and Tomas G. Villa | | 269 | | | | Index | | 279 |
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