Estrogens and Human Diseases

Estrogens may play a role, not only in classical endocrine-related tumors, such as breast or prostate, but also in several other human nosological entities, including neurodegenerative disorders, cardiovascular and immune-related diseases. This volume focuses on topics ranging from the impact of endogenous and exogenous estrogens on human development and cancer risk, to novel aspects in mechanisms of estrogen action, to estrogen implication in human malignancies (breast, prostate, liver), to the emerging role of estrogen in neurodegenerative disorders (Alzheimer's disease, multiple sclerosis, Parkinson's disease), to estrogen action in the cardiovascular system (including both genomic and nongenomic), to estrogen effects on cells of the immune system and their relevance to immune response and autoimmune diseases. The resulting inferences for clinics, diagnosis, prognosis, and treatment are also presented and extensively discussed. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member

ISBN 1573316695   Volumes 1 ISBN13 9781573316699 (What's this?)   Weight (grammes) 314 Publisher New York Academy of Sciences   Published in New York Imprint New York Academy of Sciences   Series ISSN 0077-892 Format Paperback   Series title Annals of the New York Academy of Sciences Publication date 09 Feb 2007   Height (mm) 228 Library of Congress 2006033052   Width (mm) 153 DEWEY 616.80461   Spine width (mm) 15 DEWEY edition DC22   Academic level Professional / Scholarly Pages 400

		Inside cancer complexity by Luisa M. Massimo
		In tribute to Luigi Castagnetta - drawings : a narrative approach for children with cancer by Luisa M. Massimo and Daniela A. Zarri
		The role of estrogens in normal and abnormal development of the prostate gland by Gail S. Prins and Liwei Huang and Lynn Birch and Yongbing Pu		1
		Timing of dietary estrogenic exposures and breast cancer risk by Sonia De Assis and Leena Hilakivi-Clarke		14
		From adult stem cells to cancer stem cells : Oct-4 gene, cell-cell communication, and hormones during tumor promotion by James E. Trosko		36
		Chromatin remodeling and control of cell proliferation by progestins via cross talk of progesterone receptor with the estrogen receptors and kinase signaling pathways by Guillermo P. Vicent and Cecilia Ballare and Roser Zaurin and Patricia Saragueta and Miguel Beato		59
		The role of flow cytometric immunophenotyping in myelodysplastic syndromes by Guido Pagnucco and Caterina Giambanco and Francesco Gervasi		383
		Clinical relevance of cytogenetics in myelodysplastic syndromes by Paolo Bernasconi and Marina Boni and Paola Maria Cavigliano and Silvia Calatroni and Ilaria Giardini and Barbara Rocca and Rita Zappatore and Irene Dambruoso and Marilena Caresana		395
		Genetic abnormalities as targets for molecular therapies in myelodysplastic syndromes by Daniela Cilloni and Emanuela Messa and Francesca Messa and Sonia Carturan and Ilaria Defilippi and Francesca Arruga and Valentina Rosso and Renata Catalano and Enrico Bracco and Paolo Nicoli and Giuseppe Saglio		411
		Rapid estrogen actions in the cardiovascular system by Tommaso Simoncini and Paolo Mannella and Andrea Riccardo Genazzani		424
		Estrogens in human vascular diseases by Mariam Klouche		431
		Implications of recent clinical trials of postmenopausal hormone therapy for management of cardiovascular disease by Jacques E. Rossouw		444
		Association between the polymorphism of CCR5 and Alzheimer's disease : results of a study performed on male and female patients from Northern Italy by Carmela Rita Balistreri and Maria Paola Grimaldi and Sonya Vasto and Florinda Listi and Martina Chiappelli and Federico Licastro and Domenico Lio and Calogero Caruso and Giuseppina Candore		454
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