Fundamentals of Contemporary Mass Spectrometry

Modern mass spectrometry - the instrumentation and applications in diverse fields Mass spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral part of proteomics and drug discovery process. Fundamentals of Contemporary Mass Spectrometry gives readers a concise and authoritative overview of modern mass spectrometry instrumentation, techniques, and applications, including the latest developments. After an introduction to the history of mass spectrometry and the basic underlying concepts, it covers:* Instrumentation, including modes of ionization, condensed phase ionization techniques, mass analysis and ion detection, tandem mass spectrometry, and hyphenated separation techniques* Organic and inorganic mass spectrometry* Biological mass spectrometry, including the analysis of proteins and peptides, oligosaccharides, lipids, oligonucleotides, and other biological materials* Applications to quantitative analysis Based on proven teaching principles, each chapter is complete with a concise overview, highlighted key points, practice exercises, and references to additional resources. Hints and solutions to the exercises are provided in an appendix. To facilitate learning and improve problem-solving skills, several worked-out examples are included. This is a great textbook for graduate students in chemistry, and a robust, practical resource for researchers and scientists, professors, laboratory managers, technicians, and others. It gives scientists in diverse disciplines a practical foundation in modern mass spectrometry.

ISBN 0471682292   Volumes 1 ISBN13 9780471682295 (What's this?)   Weight (grammes) 976 Publisher John Wiley and Sons Ltd   Published in Chicester Imprint Wiley-Blackwell (an imprint of John Wiley & Sons Ltd)   Series ISSN 16 Format Hardback   Series title Wiley-Interscience Series on Mass Spectrometry Publication date 18 May 2007   Height (mm) 236 Library of Congress 2006027635   Width (mm) 163 DEWEY 543.65   Spine width (mm) 34 DEWEY edition DC22   Academic level Professional / Scholarly Pages 608   Alternative ISBN 9780470118498

1		Basics of mass spectrometry		3
2		Modes of ionization		15
3		Mass analysis and ion detection		67
4		Tandem mass spectrometry		119
5		Hyphenated separation techniques		151
6		Organic mass spectrometry		197
7		Inorganic mass spectrometry		263
8		Proteins and peptides : structure determination		289
9		Proteins and peptides : posttranslational modifications		343
10		Proteins and peptides : higher-order structures		379
11		Characterization of oligosaccharides		397
12		Characterization of lipids		423
13		Structure determination of oligonucleotides		453
14		Quantitative analysis		485
15		Miscellaneous topics		501

"It presents a well written, informative, and welcome addition to the selection of textbooks on the topic." (Analytical Science and Bioanalytical Chemistry, August 2007) "The book will be a good teaching tool of the principles of mass spectrometry to undergraduates and graduates." (International Journal of Environmental and Analytical Chemistry, 2008)

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