Methods in Pain Research

In the past two decades, pain research has become one of the most rapidly growing areas of neuroscience activity. Methods in Pain Research brings together in a single volume a survey of the methods that can be used to study a reaction or 'sensory report' in humans that can only be inferred by indirect means in animal or tissues studies. It presents source material, useful advice, and guidance to specific details as well as examples of current usage. With each topic presented by one or more of the leading experts in the field, it examines the major modern techniques used in studying pain, including gene linkage, brain imaging methods, the use of transgenic rodent models, painful sensory neuropathy models, and more. The material also covers conventional methods of pain study, such as anatomical and electophysiological techniques. Methods in Pain Research provides up-to-date methodology and a guide to the strategies of experimental design.

ISBN 0849300355   Volumes 1 ISBN13 9780849300356 (What's this?)   Weight (grammes) 635 Publisher Taylor & Francis Inc   Published in Bosa Roca Imprint CRC Press Inc   Series editor Nicolelis, Miguel A.L., Simon, Sidney A. Format Hardback   Series title Frontiers in Neuroscience Publication date 22 Jun 2001   Height (mm) 235 Library of Congress 01025410   Width (mm) 156 DEWEY 616.0472   Spine width (mm) 24 DEWEY edition DC21   Academic level Undergraduate, Postgraduate, Professional / Scholarly Pages 336

Ch. 1		The Idiosyncratic Problems Associated with Pain Research by Lawrence Kruger		1
Ch. 2		Assessing Nociception in Murine Subjects by Jeffrey S. Mogil and Sonya G. Wilson and You Wan		11
Ch. 3		Techniques for Mutagenesis of the Murine Opioid System in Vivo by Michael D. Hayward and Malcolm J. Low		41
Ch. 4		Animal Models of Pain by Gary J. Bennett		67
Ch. 5		Method in Visceral Pain Research by Timothy J. Ness and Gerald F. Gebhart		93
Ch. 6		The Cytokine Challenge: Methods for the Detection of Central Cytokines in Rodent Models of Persistent Pain by Sarah M. Sweitzer and Janice L. Arruda and Joyce A. DeLeo		109
Ch. 7		Extracellular Sampling Techniques by Igor Spigelman and Yoshizo Matsuka and John K. Neubert		133
Ch. 8		Electrophysiological Recording Techniques in Pain Research by Igor Spigelman and Michael S. Gold and Alan R. Light		147
Ch. 9		Membrane Properties: Ion Channels by Michael S. Gold		169
Ch. 10		Anatomical Method in Pain Research by Susan M. Carlton and Andrew Todd		187
Ch. 11		Quantitative Morphology in Relation to Long-Term Pain States: Estimates of Neuron Numbers by Richard E. Coggeshall		213
Ch. 12		Functional Brain Imaging in Humans: Methodology and Issues by Karen D. Davis		225
Ch. 13		Methods for Imaging Human Brain Pathophysiology of Chronic Pain by A. Vania Apkarian and Igor D. Grachev and Beth R. Krauss		241
Ch. 14		Methods for Induction and Assessment of Pain in Humans with Clinical and Pharmacological Examples by Thomas Graven-Nielson and Marta Sergerdahl and Peter Svensson		263
		Index		305

"The author's objective is to address methods of pain research from different angles, particularly considering the protocols developed in anesthesia and neuroscience laboratories across the world. Those objectives are clearly metIn a well-written approach, the authors address different points of pain researchThe scope is broad but the text, to-the-point. The author's expertise is expressed in the conciseness of the text, the graphic quality, the illustrations, and the explanations for the proceduresThis is an important book for neuroscience libraries and laboratories involved in the study of pain. 4 stars!" - Celso Agner, MSc, MD, Albany Medical Center, New York, USA in Doody's Notes

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