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Few cardiac disorders have generated as much controversy and discussion over the last two centuries as the floppy mitral valve (FMV)/ mitral valve proplapse (MVP)/ mitral valvular regurgitation (MVR) triad, and the mitral valve prolapse syndrome. During the past 50 years, recognition of its broad pathologic and clinical spectrum has led to the appreciation of the FMV as the central issue in the FMV/MVP/MVR story. Accordingly, the clinical phenomena and imaging characteristics inherent in the FMV/MVP/MVR triad will be best understood when reconciled with the gross morphologic, histopathologic, and molecular characteristics of the FMV complex. This book is written to cover the entire spectrum of FMV and its sequlae. The inheritance patterns, genetic studies, and development of family pedigrees; the relations of pathology and histology to FMV and clinical functional expression; and the broad range of clinical presentation, are all examined in depth. Complications (i. e. infective endocarditis, thromboembolic phenomena, arrhythmias, progressive MVR, chordae tendinae rupture, and left atrial and left ventricular dysfunction) are discussed in detail. Insights into the mechanisms of circulatory abnormalities and their impact on clinical phenomenon are also explored. Therapeutic approaches, including medical management and the indications and role of cardiac surgery, are highlighted. Finally, a clinically useful classification for FMV/MVP patients is proposed. This book will be of interest to all cardiologists, including clinical investigators, morphologists, physiologists, pathologists, surgeons, cardiac imagers, internists, family physicians, pediatricians, and nurse clinicians, and importantly, to discerning patients and individuals in search of information about the FMV/MVP/MVR triad.
| ISBN | 0879934484 | | Pages | 753 | | ISBN13 | 9780879934484 (What's this?) | | Volumes | 1 | | Publisher | John Wiley and Sons Ltd | | Weight (grammes) | 1332 | | Imprint | Blackwell Futura | | Published in | Oxford | | Format | Hardback | | Height (mm) | 238 | | Publication date | 04 May 2000 | | Width (mm) | 162 | | Library of Congress | 99058262 | | Spine width (mm) | 46 | | DEWEY | 616.12 | | Academic level | Undergraduate, Professional / Scholarly, Postgraduate | | DEWEY edition | DC21 | |
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| | | Dedication | | | | | | Acknowledgments | | | | | | The Cover | | | | | | The Editors | | | | | | Contributors | | | | | | Introduction: The Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation by C. F. Wooley and H. Boudoulas | | | | Pt. I | | The Floppy Mitral Valve: The Morphologists | | 1 | | | | Introduction: The Floppy Mitral Value: The Morphologists by C. F. Wooley and H. Boudoulas | | 2 | | Ch. 1 | | Anatomy of the Mitral Valve by A. Angelini and S. Y. Ho and G. Thiene | | 5 | | Pt. II | | Mitral Valve Function: Physiology | | 31 | | | | Introduction: Mitral Valve Function: The Physiologists by C. F. Wooley and H. Boundoulas | | 32 | | Ch. 2 | | Physiological Basis for Mitral Valve Function by R. C. Little and W. C. Little | | 37 | | Ch. 3 | | The Function of the Normal Human Mitral Valve by D. Glbson | | 59 | | Pt. III | | The Floppy Mitral Valve: The Pathologists | | 85 | | | | Introduction: Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation: The Pathologists by C. F. Wooley and H. Boudoulas | | 86 | | Ch. 4 | | Pathomorphology of Mitral Valve Prolapse by A. E. Becker and M. J. Davies | | 91 | | Ch. 5 | | The Floppy Mitral Valve: Structural and Physical Characteristics by P. B. Baker and H. Boudoulas and C. F. Wooley | | 115 | | Pt. IV | | The Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation: The Triad | | 139 | | | | Introduction: The Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation: Keys to Understanding by C. F. Wooley and H. Boudoulas | | 140 | | Ch. 6 | | The Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation: Keys to Understanding by C. F. Wooley and H. Boudoulas | | 143 | | Pt. V | | The Floppy Mitral Valve, Mitral Valve Prolapse, Mitral Valvular Regurgitation: Heritable Aspects | | 157 | | | More... | | |
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