Principles of Molecular Medicine

The second edition of "Principles of Molecular Medicine" features new discoveries have occurred in molecular medicine along with rapid technologic advances that have revolutionized the diagnosis and treatment of diseases. As in the first edition, this book includes chapters describing advances in fields paralleling traditional medical texts, and will be especially useful to specialists who are updating their education, practicing physicians interested in keeping abreast of new developments and students appropriately curious about what is known and what lies ahead. In addition, new developments in understanding biology of previously untreatable neurodegenerative diseases are included in this edition.

ISBN 1588292029   Pages 1304 ISBN13 9781588292025 (What's this?)   Volumes 1 Publisher Humana Press Inc.   Weight (grammes) 8 Imprint Humana Press Inc.   Published in Totowa, NJ Format Hardback   Height (mm) 279 Publication date 20 Jun 2006   Width (mm) 216 Library of Congress 2005034346   Spine width (mm) 56 DEWEY 616.042   Academic level Professional / Scholarly DEWEY edition DC22

I		Genetics by Terry Magnuson and James P. Evans
1		Mendelian inheritance by Bruce R. Korf		3
2		Nontraditional inheritance by Shawn E. McCandless and Suzanne B. Cassidy		9
3		Identifying causal genetic factors by Christopher I. Amos and John S. Witte and William G. Newman		19
4		Cancer genetics and molecular oncology by Sharon E. Plon		27
5		Pharmacogenetics by Renee E. Edkins and Dennis J. Cheek		34
6		Hemophilia as a model disease for gene therapy of genetic disorders by Jay Lozier		39
7		Genetic counseling by Robin L. Bennett		46
8		Animal models in biomedical research : ethics, challenges, and opportunities by Robert W. Williams		53
9		Ethical, legal, and social implications by Marcia Van Riper		61
II		Cardiology by Anthony Rosenzweig
10		Congenital heart disease by Lazaros K. Kochilas and Alvin J. Chin		69
11		Inherited cardiomyopathies by Carolyn Y. Ho and Christine E. Seidman		98
12		Heart failure : emerging concepts in excitation-contraction coupling and [beta]-adrenoceptor coupling by Clive J. Lewis and Federica del Monte and Sian E. Harding and Roger J. Hajjar		105
13		Aortic diseases by Saumya Das and James L. Januzzi, Jr. and Eric M. Isselbacher		116
14		Atherosclerotic coronary disease by Robert E. Gerszten and Anthony Rosenzweig		121
15		Lipid metabolism and coronary artery disease by Mason W. Freeman		130
16		Hypertension by Khurshed A. Katki and Donald J. DiPette		138
17		Cardiac hypertrophy by Thomas Force and Jeffrey D. Molkentin		146
18		Arrhythmias by Barry London		157
		More...

Winner of the Book of the Year Award from Doody's Health Science Book Review Journal "The selection of topics, the ability of the contributors to present complex topics in a clear, concise manner, and the format should all contribute to making this book the standard text and reference in its field. It should be in the collection of every medical library and on the bookshelf of every physician interested in keeping up with the transformation of medicine by molecular genetics." 5 Stars-Doody's Health Science Book Review Journal. "...bridge[s] the current gap between basic science and the bedside. It will thus be useful to researchers and clinicians alike. With more than 100 chapters covering a wide variety of topics, its distinguished cohort of section editors, and its abundant tables and illustrations, it provides an accessible and much needed manual to the present and the future of molecular genetics." -Francis S. Collins, MD, PhD "...a first-class reference textbook. The format of this book is easy to follow and is relevant to the way in which medicine is currently practiced. Its division into the traditional disciplines of medicine makes it easy to identify how molecular developments have enhanced our medical knowledge, diagnostic potentials and therapeutic options...The editor-in-chief, his section editors and the contributing authors should all be congratulated on a superb job." -Molecular Medicine Today "Because molecular medicine has already started to become an integral part of medical practice, there is a growing need to integrate it into the medical school curriculum and medical education in general. Principles of Molecular Medicine is well suited to serving this purpose...closing the gap between basic science and the bedside. The book is organized according to organ systems and comprises more than 120 chapters, each written by outstanding specialists...The various facets of human hereditary disorders, including genetic counseling and molecular diagnostic testing, are clearly and comprehensively presented...the book is well written and attractive...[and] is a valuable resource that will certainly appeal to clinicians, researchers, teachers, and students alike. It will also be of value to those involved in a particular area of molecular medicine who need a reference manual in which to find information on aspects of the field in which they are less familiar...a valuable reference for anyone with an interest in the achievements and the potential of molecular medicine." -Michael Gooses, MD review in the May 20, 1999 issue of the New England Journal of Medicine "...succeeds in giving a remarkable, mostly up-to-date overview of molecular medicine such as has not been available between two covers hitherto." -New England Journal of Medicine

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