It is widely recognized that the neural basis of brain function can be fully understood only by integrating many disciplines at many levels. Studies os synaptic organization are bringing about a quiet revolution in achieving this goal, as documented by this unique book over the past 30 years. In this fifth edition, the results of the mouse and human genome projects are incorporated for the first time. Molecular biologists interested in functional genomics and proteomics of the brain will find answers here to the critical questions: what are the cell and circuit functions of gene products? Also for the first time, the reader is oriented to supporting neuroscience databases. Among the new advances covered are 2-photon confocal laser microscopy of dendrites and dendritic spines, biochemical analyses, and dual patch and multielectrode recordings, applied together with an increasing range of behavioural and gene-targeting methods. Leading experts in the best understood brain regions bring together the molecular, anatomical, functional, and behavioural data in authoritative integrated accounts.The chapters are organized in the same format, covering the neural elements, synaptic connections, basic circuits, physiology, neurotransmitters, neuromodulators, membrane properties, dendritic properties, and with a final section on how the circuits mediate specific behaviours. The uniform framework for each chapter enables the authors to higlight the principles that are common to all regions, as well as the adaptations unique to each, thus serving as a model for understanding the neural basis of behaviour.
| ISBN | 019515956X | | Pages | 736 | | ISBN13 | 9780195159561
(What's this?) | | Volumes | 1 | | Publisher | Oxford University Press Inc | | Weight (grammes) | 1110 | | Imprint | Oxford University Press Inc | | Published in | New York | | Format | Paperback | | Previous ISBN | 9780195118247 | | Publication date | 01 Nov 2003 | | Height (mm) | 234 | | Library of Congress | QP376 \.S9, QP376 \.S9 | | Width (mm) | 164 | | DEWEY | 612.82 | | Spine width (mm) | 34 | | DEWEY edition | DC22 | | Academic level | Professional / Scholarly |
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| | | Contributors | | |
| 1 | | Introduction to Synaptic Circuits by Gordon M. Shepherd | | 1 |
| 2 | | Membrane Properties and Neurotransmitter Actions by David A. McCormick | | 39 |
| 3 | | Spinal Cord: Ventral Horn by Robert E. Burke | | 79 |
| 4 | | Cochlear Nucleus by Eric D. Young and Donata Oertel | | 125 |
| 5 | | Olfactory Bulb by Gordon M. Shepherd and Wei R. Chen and Charles A. Greer | | 165 |
| 6 | | Retina by Peter Sterling and Jonathan B. Demb | | 217 |
| 7 | | Cerebellum by Rodolfo R. Llinas and Kerry D. Walton and Eric J. Lang | | 271 |
| 8 | | Thalamus by S. Murray Sherman and R. W. Guillery | | 311 |
| 9 | | Basal Ganglia by Charles J. Wilson | | 361 |
| 10 | | Olfactory Cortex by Kevin R. Neville and Lewis B. Haberly | | 415 |
| 11 | | Hippocampus by Daniel Johnston and David G. Amaral | | 455 |
| 12 | | Neocortex by Rodney Douglas and Henry Markram and Kevan Martin | | 499 |
| | | References | | 559 |
| | | Index | | 705 |
From reviews of previous editions:
"This is...a reference textbook that has served generations of neuroscientists at all levels of their career for a quarter century. It is like a wise and trusted mentor, who is always there for you...The marvel of the book in all editions is how much information is packed into such a small number of pages, yet it is comprehensible...any college or university instructor who teaches neurobiology ought to read this book, for it provides a depth of knowledge and perspective that cannot be gained from a (bad) strategy of knowing the course textbook cold and staying a few chapters ahead of one's students."--Contemporary Psychology
"The book remains a staple, and should be on the shelf of any serious neuroscientist."--The Quarterly Review of Biology
"By any measure this work is a classic...It will undoubtedly take its place as one of the most significant and comprehensive commentaries of our time on structure and function of nervous ti
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